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LC kinetic stabilizer-1

Product Specifications

CAS Number

2495750-19-9

Target

Others

Related Pathways

Others

Bioactivity

LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WIL-FL represents an amyloidogenic FL LC dimer.

Smiles

CC=1C=2C(=CC(N(CC)CC)=CC2)OC(=O)C1CCNC(NCC3=CC(=CC=C3)C4=CN=CN4)=O

Molecular Formula

C27H31N5O3

Molecular Weight

473.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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