LC kinetic stabilizer-1
Product Specifications
CAS Number
2495750-19-9
Target
Others
Related Pathways
Others
Bioactivity
LC kinetic stabilizer-1 is a potent, selective kinetic stabilizer for amyloidogenic immunoglobulin light chains, demonstrating EC50 values of 140 nM for WIL-FL* and 74.1 nM for WIL-FL*T46L/F49Y, respectively. Notably, WIL-FL represents an amyloidogenic FL LC dimer.
Smiles
CC=1C=2C(=CC(N(CC)CC)=CC2)OC(=O)C1CCNC(NCC3=CC(=CC=C3)C4=CN=CN4)=O
Molecular Formula
C27H31N5O3
Molecular Weight
473.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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