PBT434 methanesulfonate
Product Specifications
CAS Number
2387898-69-1
Target
Others
Related Pathways
Others
Bioactivity
PBT434 methanesulfonate is an orally active, potent α-synuclein aggregation inhibitor with the ability to cross the blood-brain barrier. Acting as an iron chelator, it modulates transcellular iron trafficking, inhibits iron-mediated redox activity, and prevents iron-mediated aggregation of α-synuclein. PBT434 methanesulfonate also safeguards against the loss of substantia nigra pars compacta neurons (SNpc), showing promise for Parkinson's disease (PD) research.
Smiles
O=C1C=2C(Cl)=CC(Cl)=C(O)C2N=C(N1C)CNCC.O=S(=O)(O)C
Molecular Formula
C13H17Cl2N3O5S
Molecular Weight
398.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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