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PBT434 methanesulfonate

Product Specifications

CAS Number

2387898-69-1

Target

Others

Related Pathways

Others

Bioactivity

PBT434 methanesulfonate is an orally active, potent ?-synuclein aggregation inhibitor with the ability to cross the blood-brain barrier. Acting as an iron chelator, it modulates transcellular iron trafficking, inhibits iron-mediated redox activity, and prevents iron-mediated aggregation of ?-synuclein. PBT434 methanesulfonate also safeguards against the loss of substantia nigra pars compacta neurons (SNpc), showing promise for Parkinson's disease (PD) research.

Smiles

O=C1C=2C(Cl)=CC(Cl)=C(O)C2N=C(N1C)CNCC.O=S(=O)(O)C

Molecular Formula

C13H17Cl2N3O5S

Molecular Weight

398.26

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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