CM-579 trihydrochloride
Product Specifications
Target
DNA Methyltransferase, Histone Methyltransferase, Others
Related Pathways
Others, Chromatin/Epigenetic
Bioactivity
CM-579 trihydrochloride, a first-in-class reversible, dual inhibitor of G9a and DNMT, exhibits potent in vitro cellular activity across a broad spectrum of cancer cells. It demonstrates inhibition with IC50 values of 16 nM for G9a and 32 nM for DNMT, respectively.
Smiles
CC1=CC=C(O1)C2=NC3=CC(=C(C=C3C(=C2)NCC4CCN(CC4)C)OC)OCCCN5CCCC5.Cl.Cl.Cl
Molecular Formula
C29H43Cl3N4O3
Molecular Weight
602.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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