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Bicuculline methobromide

Product Specifications

CAS Number

66016-70-4

Target

Others

Related Pathways

Others

Bioactivity

Bicuculline methobromide is a selective GABAA receptor antagonist with an IC50 of 3 μM. It can induce clonic-tonic seizures in mammals and block Ca2+-activated potassium channels, commonly used to establish models of epilepsy and related neurological disorders.

Smiles

C[N+]1(C)[C@]([C@]2(C3=C(C(=O)O2)C4=C(C=C3)OCO4)[H])(C5=C(C=C6C(=C5)OCO6)CC1)[H].[Br-]

Molecular Formula

C21H20BrNO6

Molecular Weight

462.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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