DYRKs-IN-1 hydrochloride
Product Specifications
CAS Number
1386980-55-7
Target
Others, DYRK
Related Pathways
Tyrosine Kinase/Adaptors, Others, Cell Cycle/Checkpoint
Bioactivity
DYRKs-IN-1 hydrochloride is a potent inhibitor of Dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs), with IC50 values of 5 nM for DYRK1A and 8 nM for DYRK1B, and exhibits antitumor activity.
Smiles
Cl.O=C1N=C2NC(=NC=C2C=C1C(=O)NC3=CC(=CC=C3Cl)C(=O)NC(C=4C=CC=CC4)CCN)N5CC6OC(C5)CC6
Molecular Formula
C30H31Cl2N7O4
Molecular Weight
624.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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