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DYRKs-IN-1 hydrochloride

Product Specifications

CAS Number

1386980-55-7

Target

Others, DYRK

Related Pathways

Tyrosine Kinase/Adaptors, Others, Cell Cycle/Checkpoint

Bioactivity

DYRKs-IN-1 hydrochloride is a potent inhibitor of Dual-specificity tyrosine-phosphorylation-regulated kinases (DYRKs), with IC50 values of 5 nM for DYRK1A and 8 nM for DYRK1B, and exhibits antitumor activity.

Smiles

Cl.O=C1N=C2NC(=NC=C2C=C1C(=O)NC3=CC(=CC=C3Cl)C(=O)NC(C=4C=CC=CC4)CCN)N5CC6OC(C5)CC6

Molecular Formula

C30H31Cl2N7O4

Molecular Weight

624.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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