Pyridostatin hydrochloride
Product Specifications
CAS Number
1781882-65-2
Target
Others, DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair
Bioactivity
Pyridostatin (RR82) hydrochloride, a G-quadruplex DNA stabilizing agent (Kd = 490 nM), induces replication- and transcription-dependent DNA damage, promoting growth arrest in human cancer cells. It specifically targets the proto-oncogene Src, leading to reduced SRC protein levels and decreased SRC-dependent cellular motility in human breast cancer cells.
Smiles
Cl.Cl.Cl.Cl.Cl.NCCOc1cc(nc(c1)C(=O)Nc1cc(OCCN)c2ccccc2n1)C(=O)Nc1cc(OCCN)c2ccccc2n1
Molecular Formula
C31H37Cl5N8O5
Molecular Weight
778.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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