P-CAB agent 2 hydrochloride
Product Specifications
CAS Number
2209911-80-6
Target
Potassium Channel, Others
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
P-CAB agent 2 hydrochloride is a potent, orally active potassium-competitive acid blocker (P-CAB) and gastric acid secretion inhibitor. It effectively inhibits H+/K+-ATPase activity, with an IC50 value of <100 nM, and targets the hERG potassium channel with an IC50 value of 18.69 μM. Moreover, P-CAB agent 2 hydrochloride demonstrates no acute toxicity and effectively inhibits histamine-induced gastric acid secretion [1].
Smiles
Cl.O=S(=O)(C=1C=CC=C(OCCCOC)C1)N2C=C(C=C2C=3C=CC=CC3F)CNC
Molecular Formula
C22H26ClFN2O4S
Molecular Weight
468.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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