Topoisomerase IV inhibitor 2
Selected Variant
T72154-01
Size: 25 mg
Product Specifications
CAS Number
2883403-36-7
Target
Topoisomerase, Antibacterial
Related Pathways
DNA Damage/DNA Repair, Microbiology/Virology
Bioactivity
Topoisomerase IV inhibitor 2 (compound 5d) is a potent inhibitor of DNA topoisomerase IV (TOPO IV), exhibiting IC50 values of 0.35 μM for TOPO IV and 0.55 μM for DNA gyrase. It demonstrates antibacterial properties with minimum inhibitory concentrations (MICs) of 1.985 μM against Staphylococcus aureus Newman and 0.744 μM against Escherichia coli ATCC8739 [1].
Smiles
C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCN(CC4)CC(=O)NC5=CC=C(C=C5)S(=O)(=O)NC6=NC7=CC=CC=C7N=C6)F)C(=O)O
Molecular Formula
C33H30FN7O6S
Molecular Weight
671.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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