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Montelukast dicyclohexylamine

Product Specifications

CAS Number

577953-88-9

Target

Others, Leukotriene Receptor

Related Pathways

GPCR/G Protein, Others

Bioactivity

Montelukast dicyclohexylamine (MK0476), a potent, selective, and orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLT1), is utilized in the research of asthma, liver injury, and COVID-19. It exhibits antioxidant properties in the context of intestinal ischemia-reperfusion injury and can mitigate cardiac damage. Additionally, it reduces eosinophil infiltration in the airways of asthmatic patients.

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N(C1CCCCC1)C2CCCCC2.C(S[C@H](CCC1=C(C(C)(C)O)C=CC=C1)C2=CC(/C=C/C3=NC4=C(C=C3)C=CC(Cl)=C4)=CC=C2)C5(CC(O)=O)CC5

Molecular Formula

C47H59ClN2O3S

Molecular Weight

767.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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