Montelukast dicyclohexylamine
Product Specifications
CAS Number
577953-88-9
Target
Others, Leukotriene Receptor
Related Pathways
GPCR/G Protein, Others
Bioactivity
Montelukast dicyclohexylamine (MK0476), a potent, selective, and orally active antagonist of the cysteinyl leukotriene receptor 1 (CysLT1), is utilized in the research of asthma, liver injury, and COVID-19. It exhibits antioxidant properties in the context of intestinal ischemia-reperfusion injury and can mitigate cardiac damage. Additionally, it reduces eosinophil infiltration in the airways of asthmatic patients.
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N(C1CCCCC1)C2CCCCC2.C(S[C@H](CCC1=C(C(C)(C)O)C=CC=C1)C2=CC(/C=C/C3=NC4=C(C=C3)C=CC(Cl)=C4)=CC=C2)C5(CC(O)=O)CC5
Molecular Formula
C47H59ClN2O3S
Molecular Weight
767.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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