Methotrexate α-tert-butyl ester
Product Specifications
CAS Number
79640-70-3
Target
Others, DNA/RNA Synthesis, Antifolate
Related Pathways
DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint
Purity
0.86865
Bioactivity
Methotrexate α-tert-butyl ester is a protected analog of the antineoplastic and immunosuppressive drug methotrexate (MTX), in which the β-carboxyl group of the L-glutamate moiety is esterified with a tert-butyl group. Methotrexate α-tert-butyl ester is primarily used in chemical synthesis and prodrug development studies.
Smiles
NC=1C2=C(N=C(N)N1)N=CC(CN(C)C3=CC=C(C(N[C@H](C(OC(C)(C)C)=O)CCC(O)=O)=O)C=C3)=N2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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