(+) -Norfenfluramine hydrochloride
Product Specifications
CAS Number
37936-89-3
Target
5-HT Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
(+) -Norfenfluramine hydrochloride, a significant liver metabolite of (+) -fenfluramine, functions as a selective agonist for the 5-HT 2B receptor (K i: 11.2 nM), effectively stimulating inositol phosphate hydrolysis and elevating intracellular Ca2+. It is utilized in research focusing on primary pulmonary hypertension and valvular heart disease.
Smiles
Cl.C[C@H](N)Cc1cccc(c1)C(F)(F)F
Molecular Formula
C10H13ClF3N
Molecular Weight
239.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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