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(+) -Norfenfluramine hydrochloride

Product Specifications

CAS Number

37936-89-3

Target

5-HT Receptor

Related Pathways

Neuroscience|||GPCR/G Protein

Bioactivity

(+) -Norfenfluramine hydrochloride, a significant liver metabolite of (+) -fenfluramine, functions as a selective agonist for the 5-HT 2B receptor (K i: 11.2 nM), effectively stimulating inositol phosphate hydrolysis and elevating intracellular Ca2+. It is utilized in research focusing on primary pulmonary hypertension and valvular heart disease.

Smiles

Cl.C[C@H](N)Cc1cccc(c1)C(F)(F)F

Molecular Formula

C10H13ClF3N

Molecular Weight

239.67

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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