Atorvastatin hemicalcium trihydrate

Product Specifications

CAS Number

344920-08-7

Target

Autophagy|||HMG-CoA Reductase|||Others

Related Pathways

Autophagy|||Others|||Metabolism

Bioactivity

Atorvastatin Hemicalcium Trihydrate, an orally active HMG-CoA reductase inhibitor, effectively reduces blood lipids. It also inhibits human SV-SMC proliferation and invasion, showing IC50 values of 0.39 ?M and 2.39 ?M, respectively.

Smiles

O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.O=C(C5=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C6=CC=C(C=C6)F)=C5C7=CC=CC=C7)NC8=CC=CC=C8.[Ca+2].O.O.O.O.O.O