What is the catalog number for FM04?

The catalog number for FM04 is T72055.

What sizes are available for FM04?

FM04 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does FM04 come in?

FM04 is available in 6 different pack sizes.

FM04 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FM04?

FM04 is manufactured by Molfinity.

What is the estimated delivery time for FM04?

Estimated delivery time for FM04 is approximately 10 business day(s), depending on your location.

FM04

Product Specifications

CAS Number

1807320-40-6

Target

P-gp

Related Pathways

Neuroscience, Membrane transporter/Ion channel

Purity

0.9987

Bioactivity

FM04 is an orally active and highly potent inhibitor of P-glycoprotein (P-gp) with an EC50 value of 83 nM. FM04 can interact with Q1193 and I1115 in human P-gp nucleotide binding domain 2 (NBD2) . Thereby disrupting the R262-Q1081-Q1118 interaction pocket and uncoupling the ICL2-NBD2 interaction, thereby inhibiting P-gp. FM04 can be used in the treatment of cancer and tumors.