673-A
Product Specifications
CAS Number
109437-62-9
Target
Dehydrogenase, Necroptosis, Mitochondrial Metabolism, Others
Related Pathways
Apoptosis, Metabolism, Others
Bioactivity
673-A is an aldehyde dehydrogenase (ALDH1A) inhibitor that depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines. 673-A triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP) . 673-A also overcomes chemotherapy resistance in vivo.
Smiles
O=CC1=CC=C(C=C1)N1CC2=CC=CC=C2C1
Molecular Formula
C15H13NO
Molecular Weight
223.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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