Gilteritinib hemifumarate
Product Specifications
CAS Number
1254053-84-3
Target
FLT, TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9978
Bioactivity
Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of relapsed or refractory FLT3 mutant AML.
Smiles
C(=C/C(O)=O)\C(O)=O.N(C=1C(C(N)=O)=NC(CC)=C(NC2CCOCC2)N1)C3=CC(OC)=C(C=C3)N4CCC(CC4)N5CCN(C)CC5
Molecular Formula
C29H44N8O3.1/2C4H4O4
Molecular Weight
610.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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