Gilteritinib hemifumarate

Product Specifications

CAS Number

1254053-84-3

Target

FLT|||TAM Receptor

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis

Purity

0.9978

Bioactivity

Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of relapsed or refractory FLT3 mutant AML.

Smiles

C(=C/C(O)=O)\C(O)=O.N(C=1C(C(N)=O)=NC(CC)=C(NC2CCOCC2)N1)C3=CC(OC)=C(C=C3)N4CCC(CC4)N5CCN(C)CC5

Molecular Formula

C29H44N8O3.1/2C4H4O4

Molecular Weight

610.75

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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