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N-Fmoc-8-aminooctanoic acid

Product Specifications

CAS Number

126631-93-4

Target

Others, PROTAC Linker

Related Pathways

Others, PROTAC

Bioactivity

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Smiles

C(OC(NCCCCCCCC(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Molecular Formula

C23H27NO4

Molecular Weight

381.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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