APKC-I
Product Specifications
CAS Number
15854-12-3
Target
Others, PKC
Related Pathways
Others, Cytoskeletal Signaling, Chromatin/Epigenetic
Bioactivity
APKC-I is an inhibitor of atypical protein kinase C (aPKC) which inhibits both PKCζ and PKCι with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemia-reperfusion (IR) -induced permeability.
Smiles
CCOC(=O)C1=C(N)SC=C1C1=CC(OC)=C(OC)C=C1
Molecular Formula
C15H17NO4S
Molecular Weight
307.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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