Isonanangenine B
Product Specifications
CAS Number
1623153-14-9
Target
Others
Related Pathways
Others
Bioactivity
Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 μM. Isonanagenine B (18.42 μM) inhibits STAT3 and NF-κB binding to the survivin promoter in chromatin immunoprecipitation (ChIP) assays. It also induces apoptosis in COLO 320DM cells.
Smiles
[H][C@@]12[C@H](OC(=O)CCCCC)C=C3C(=O)OC[C@]3(O)[C@@]1(C)[C@H](O)CCC2(C)C
Molecular Formula
C21H32O6
Molecular Weight
380.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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