NU1085
Product Specifications
CAS Number
188106-83-4
Target
Others
Related Pathways
Others
Bioactivity
NU1085 is a potent poly (ADP-ribose) polymerase (PARP) inhibitors have been developed that potentiate the cytotoxicity of ionizing radiation and anticancer drugs. The biological effects of NU1085 [Ki = 6 nM], in combination with temozolomide (TM) or topotecan (TP) have been studied in 12 human tumor cell lines (lung, colon, ovary, and breast cancer) . Cells were treated with increasing concentrations of TM or TP +/- NU1085 (10 microM) for 72 h.
Smiles
NC(=O)c1cccc2nc([nH]c12)-c1ccc(O)cc1
Molecular Formula
C14H11N3O2
Molecular Weight
253.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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