GTP-14564
Product Specifications
CAS Number
34823-86-4
Target
Tyrosine Kinases, FLT
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9981
Bioactivity
GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 μ m, whereas a 30-fold higher concentration of GTP-14564 is required to inhibit the FLT3 ligand-dependent growth (wt-FLT3) of Ba/F3 expressing wild-type FLT3. F3 expressing wild-type FLT3 (wt-FLT3) .
Smiles
C12=C(C=3C(O1)=CC=CC3)NN=C2C4=CC=CC=C4
Molecular Formula
C15H10N2O
Molecular Weight
234.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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