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Lig4-4

Product Specifications

CAS Number

3598-68-3

Target

Others

Related Pathways

Others

Bioactivity

Lig4-4 is a TREK-1 current inhibitor (IC50 = 2.06??M) that has demonstrated potential for use as a protective agent against cerebral ischemia. It has been postulated that the neuroprotective effects of Lig4-4 against cerebral ischemia may be attributed to the modulation of Bcl-2 and cleaved-caspase-3 expression, leading to the inhibition of neuronal apoptosis.

Smiles

[O-][N+](=O)CC1OC(=O)C2=CC=CC=C12

Molecular Formula

C9H7NO4

Molecular Weight

193.16

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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