Lig4-4
Product Specifications
CAS Number
3598-68-3
Target
Others
Related Pathways
Others
Bioactivity
Lig4-4 is a TREK-1 current inhibitor (IC50 = 2.06 μM) that has demonstrated potential for use as a protective agent against cerebral ischemia. It has been postulated that the neuroprotective effects of Lig4-4 against cerebral ischemia may be attributed to the modulation of Bcl-2 and cleaved-caspase-3 expression, leading to the inhibition of neuronal apoptosis.
Smiles
[O-][N+](=O)CC1OC(=O)C2=CC=CC=C12
Molecular Formula
C9H7NO4
Molecular Weight
193.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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