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Deserpidine hydrochloride

Product Specifications

CAS Number

6033-69-8

Target

Others, Angiotensin-converting Enzyme (ACE)

Related Pathways

Metabolism, Others

Bioactivity

Deserpidine hydrochloride is the salf form of Deserpidine (free base), which is an antihypertensive drug related to reserpine which occurs naturally in Rauwolfia canescens. Deserpidine is a competitive inhibitor of the angiotensin converting enzyme (ACE) . By competing with angiotensin I for ACE, deserpidine blocks the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor. Reduced level of serum angiotensin II causes a decrease in blood pressure. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.

Smiles

CCC(CC)C1C2=C(NN=C2C2=CC=CC=C2)OC(N)=C1C#N

Molecular Formula

C32H39ClN2O8

Molecular Weight

615.12

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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