CB10-277
Product Specifications
CAS Number
7203-91-0
Target
Others, DNA Alkylator/Crosslinker, Nucleoside Antimetabolite/Analog
Related Pathways
Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alkylates DNA, resulting in inhibition of DNA replication and repair; in addition, this agent may act as a purine analogue, resulting in inhibition of DNA synthesis, and may interact with protein sulfhydryl groups.
Smiles
CN(C)\N=N\C1=CC=C(C=C1)C(O)=O
Molecular Formula
C9H11N3O2
Molecular Weight
193.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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