Pirarubicin HCl
Product Specifications
CAS Number
95343-20-7
Target
Antibacterial, Topoisomerase, Antibiotic, Autophagy, Others
Related Pathways
DNA Damage/DNA Repair, Others, Autophagy, Microbiology/Virology
Bioactivity
Pirarubicin HCl is the hydrochloride salt form of pirarubicin, an analogue of the anthracycline antineoplastic antibiotic doxorubicin with antineoplastic activity. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.
Smiles
Cl.[H][C@]1(CCCCO1)O[C@H]1[C@@H](N)C[C@]([H])(O[C@H]2C[C@@](O)(Cc3c(O)c4C(=O)c5cccc(OC)c5C(=O)c4c(O)c23)C(=O)CO)O[C@H]1C
Molecular Formula
C32H38ClNO12
Molecular Weight
664.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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