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GB1874

Product Specifications

CAS Number

1011440-46-2

Target

Wnt/beta-catenin

Related Pathways

Cytoskeletal Signaling, Stem Cells

Bioactivity

GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation and stemness in Wnt-dependent colorectal cancer (CRC) cells and inhibiting the growth of HCT116 tumour xenografts in vivo.

Smiles

O=C1CCCC1SC2=NN=C(N2C(C=3C=CC=CC3)C)COC4=CC=C(C=C4)CC

Molecular Formula

C24H27N3O2S

Molecular Weight

421.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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