GB1874
Product Specifications
CAS Number
1011440-46-2
Target
Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling|||Stem Cells
Bioactivity
GB1874 is an inhibitor of the Wnt pathway targeting ?-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation and stemness in Wnt-dependent colorectal cancer (CRC) cells and inhibiting the growth of HCT116 tumour xenografts in vivo.
Smiles
O=C1CCCC1SC2=NN=C(N2C(C=3C=CC=CC3)C)COC4=CC=C(C=C4)CC
Molecular Formula
C24H27N3O2S
Molecular Weight
421.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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