Endoxifen mesylate
Product Specifications
CAS Number
1032008-71-1
Target
Others
Related Pathways
Others
Bioactivity
Endoxifen, also known as N-desmethyl-4-hydroxytamoxifen, is a chemical that is under development for estrogen receptor-positive breast cancer. It is also being evaluated as an antipsychotic for treatment of mania and other psychotic disorders. Endoxifen is a nonsteroidal selective estrogen receptor modulator (SERM) of the triphenylethylene group. It is an active metabolite of tamoxifen and has been found to be effective in patients that have failed previous hormonal therapies (tamoxifen, aromatase inhibitors, and fulvestrant) . The prodrug tamoxifen is metabolized by the CYP2D6 enzyme to produce afimoxifene (4-hydroxytamoxifen) and endoxifen.
Smiles
S(C)(=O)(=O)O.C(=C(/CC)\C1=CC=CC=C1)(\C2=CC=C(OCCNC)C=C2)/C3=CC=C(O)C=C3
Molecular Formula
C26H31NO5S
Molecular Weight
469.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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