CIA-1 hcl (452087-38-6 Free base)
Product Specifications
CAS Number
1049691-47-5
Target
Others, Orphan Receptor, Gamma-secretase
Related Pathways
Neuroscience, Stem Cells, Others, Proteases/Proteasome, GPCR/G Protein
Purity
0.9902
Bioactivity
CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.
Smiles
Cl.N=1C=NC(NCCC2=CC=C(OC)C(OC)=C2)=C3C=C(SC13)C
Molecular Formula
C17H20ClN3O2S
Molecular Weight
365.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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