Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LEQ-506

Product Specifications

CAS Number

1057677-92-5

Target

Hedgehog/Smoothened, Others

Related Pathways

GPCR/G Protein, Others, Stem Cells

Bioactivity

LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh) -ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth.

Smiles

C(C=1C2=C(C(=NN1)N3CCN(CC3)C4=CC=C(C(C)(C)O)C=N4)C=CC=C2)C5=CC=CC=C5

Molecular Formula

C27H29N5O

Molecular Weight

439.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Lipin 2 (LPIN2) (NM_014646) Human Tagged ORF Clone Lentiviral Particle
RC224070L1V 200 µL

Lipin 2 (LPIN2) (NM_014646) Human Tagged ORF Clone Lentiviral Particle

Sign In for Pricing
View Details
Rabbit Polyclonal DEFB129 Antibody
NBP2-68588-25ul 25 µL

Rabbit Polyclonal DEFB129 Antibody

Sign In for Pricing
View Details
Rno-let-7b-3p miRNA Agomir
CMS0242-01 5 nmol

Rno-let-7b-3p miRNA Agomir

Sign In for Pricing
View Details
Rno-let-7b-3p miRNA Agomir
CMS0242-02 10 nmol

Rno-let-7b-3p miRNA Agomir

Sign In for Pricing
View Details
Rno-let-7b-3p miRNA Agomir
CMS0242-03 20 nmol

Rno-let-7b-3p miRNA Agomir

Sign In for Pricing
View Details
Caspase-7 p20 Rabbit Polyclonal Antibody
E53P02123 100 µL

Caspase-7 p20 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details