KAL-21404358
Product Specifications
CAS Number
1065573-84-3
Target
Others, Ligands for Target Protein for PROTAC
Related Pathways
Others, PROTAC
Bioactivity
KAL-21404358 is a Novel allosteric inhibitor of K-RasG12D, binding to the P110 site of K-RasG12D, impairing the K-RasG12D interaction with B-Raf, and disrupting the RAF-MEK-ERK and the PI3K-AKT signaling pathway.
Smiles
OC=1C2=C(N=C(CN3CC(CCO)N(CC(C)(C)C)CC3)C1)C=CC=C2
Molecular Formula
C21H31N3O2
Molecular Weight
357.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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