Palifosfamide tromethamine
Product Specifications
CAS Number
1070409-31-2
Target
Others, DNA Alkylator/Crosslinker
Related Pathways
Others, DNA Damage/DNA Repair
Bioactivity
Palifosfamide (tromethamine), a synthetically derived alkylating agent, exhibits potential antineoplastic properties. Acting as the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA at GC base pairs, inhibiting DNA replication and inducing cell death. Palifosfamide (tromethamine) boasts reduced toxicity in comparison to ifosfamide.
Smiles
O=P(O)(NCCCl)NCCCl.OCC(N)(CO)CO
Molecular Formula
C8H22Cl2N3O5P
Molecular Weight
342.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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