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Streptonigrin (racemate)

Product Specifications

CAS Number

1079893-79-0

Target

Antibiotic, PAD, Others

Related Pathways

Microbiology/Virology, Others, Chromatin/Epigenetic

Bioactivity

Streptonigrin is an aminoquinone antitumor and antibacterial antibiotic produced by Streptomyces flocculus. Streptonigrin inhibits β-Catenin/Tcf signaling and shows cytotoxicity in β-catenin-activated cells. Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells. Note: Streptonigrin from natural resource is (-) -rotation, has CAS#3930-19-6 and is a R-isomer.

Smiles

NC=1C(=C(C)C(C(O)=O)=NC1C=2N=C3C(=CC2)C(=O)C(OC)=C(N)C3=O)C4=C(O)C(OC)=C(OC)C=C4

Molecular Formula

C25H22N4O8

Molecular Weight

506.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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