Plogosertib
Product Specifications
CAS Number
1137212-79-3
Target
PLK
Related Pathways
Cell Cycle/Checkpoint
Purity
>99.99%
Bioactivity
Plogosertib (CYC140) is an orally active, selective, potent, and ATP-competitive PLK1 inhibitor with an IC50 value of 3 nM.Plogosertib exhibits antiproliferative and anticancer activity and can be used for the study of solid and hematologic tumors. and hematologic tumors.
Smiles
O=C1C2(CN(C=3C(N1C)=CN=C(NC4=C(OC)C=C(C(N[C@@H]5CC[C@H](CC5)N6CCN(C)CC6)=O)C=C4)N3)C7CCCC7)CC2
Molecular Formula
C34H48N8O3
Molecular Weight
616.797
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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