RO5126946
Product Specifications
CAS Number
1137233-79-4
Target
Others
Related Pathways
Others
Bioactivity
RO5126946 is a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator. RO5126946 allosterically modulates α7nAChR activity. RO5126946 increased acetylcholine-evoked peak current and delayed current decay but did not affect the recovery of α7nAChRs from desensitization. In addition, RO5126946's effects were absent when nicotine-evoked currents were completely blocked by coapplication of the α7nAChR-selective antagonist methyl-lycaconitine.
Smiles
N(C(=O)C1=C(OC)C=CC(Cl)=C1)[C@H]2[C@@H](C2(C)C)C3=CC=C(S(N)(=O)=O)C=C3
Molecular Formula
C19H21ClN2O4S
Molecular Weight
408.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
AP14838PU-N 400 µL
TAK1 (MAP3K7) (C-term) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details 
TRC-A611840-250MG 250 mg
5-Amino-1-(2,3-O-isopropylidene-Beta-D-ribofuranosyl)imidazole-4-carboxamide
Sign In for Pricing
View Details 
GP-1401-10 1 mL
Colloidal Gold Conjugated Lens culinaris Lectin (Lentil) -LcH-, 10nm
Sign In for Pricing
View Details 