CLT-28643
Product Specifications
CAS Number
1153631-91-4
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Purity
0.9989
Bioactivity
CLT-28643 is a potent and specific α5β1-Integrin inhibitor that prevents fibrosis in glaucoma filtration surgery (GFS), inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation in a bleomycin-induced lung fibrosis model, and improves insulin sensitivity and cardiac function in H9C2 cells from obese mice.
Smiles
O=C(O)C1=CN=C2C=CC(=CC2=C1NC3=CC=C(OC)C=C3)C(=O)NC
Molecular Formula
C19H17N3O4
Molecular Weight
351.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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