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G-479

Product Specifications

CAS Number

1168092-22-5

Target

MEK, Potassium Channel, Others

Related Pathways

Others, MAPK, Membrane transporter/Ion channel

Bioactivity

G-479 is an potent MEK inhibitor. Structurally, G-479 is an analogue of GDC-0623 (or so-call Me-Too drug) . G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.

Smiles

N(C=1N2C(C=NC1C(NOC[C@@H](CO)O)=O)=CN=C2)C3=C(F)C=C(I)C=C3

Molecular Formula

C16H15FIN5O4

Molecular Weight

487.22

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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