XL413 xHCl

Product Specifications

CAS Number

1169562-71-3

Target

Pim|||Casein Kinase|||CDK

Related Pathways

Chromatin/Epigenetic|||JAK/STAT signaling|||Metabolism|||Stem Cells|||Cell Cycle/Checkpoint

Purity

0.9967

Bioactivity

XL413 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.XL413 HCl inhibited CK2 and PIM1 with IC50 values of 215 and 42 nM, respectively.XL413 HCl showed an EC50 value of 118 against pMCM.

Smiles

Cl.Clc1ccc2oc3c(nc([nH]c3=O)[C@@H]3CCCN3)c2c1

Molecular Formula

C14H12ClN3O2.xHCl

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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