Theophylline-d6
Product Specifications
CAS Number
117490-39-8
Target
PDE, Endogenous Metabolite, Autophagy, Adenosine Receptor
Related Pathways
Metabolism, GPCR/G Protein, Neuroscience, Autophagy
Bioactivity
Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. Formulations containing theophylline have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD) .
Smiles
[2H]C([2H])([2H])n1c2nc[nH]c2c(=O)n(c1=O)C([2H])([2H])[2H]
Molecular Formula
C7H2D6N4O2
Molecular Weight
186.2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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