Metaxalone-d6
Product Specifications
CAS Number
1189944-95-3
Target
NF-κB
Related Pathways
NF-κB, Metabolism
Bioactivity
Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 μM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone have been used in the treatment of lower back pain.
Smiles
C(OC1=CC(C([2H])([2H])[2H])=CC(C([2H])([2H])[2H])=C1)C2OC(=O)NC2
Molecular Formula
C12H9D6NO3
Molecular Weight
227.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0506702 1.0 µg DNA
CRG sgRNA CRISPR Lentivector (Human) (Target 1)
Sign In for Pricing
View Details 
PC1005199-01 100 mg
(R) -2- ((tert-Butoxycarbonyl) amino) -3- (2,5-difluorophenyl) propanoic acid
Sign In for Pricing
View Details PC1005199-02 250 mg
(R) -2- ((tert-Butoxycarbonyl) amino) -3- (2,5-difluorophenyl) propanoic acid
Sign In for Pricing
View Details