Metaxalone-d6
Product Specifications
CAS Number
1189944-95-3
Target
NF-?B
Related Pathways
NF-?B|||Metabolism
Bioactivity
Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-?, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone have been used in the treatment of lower back pain.
Smiles
C(OC1=CC(C([2H])([2H])[2H])=CC(C([2H])([2H])[2H])=C1)C2OC(=O)NC2
Molecular Formula
C12H9D6NO3
Molecular Weight
227.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
