GNE-900
Product Specifications
CAS Number
1200126-26-6
Target
Apoptosis, Chk
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Purity
0.992
Bioactivity
GNE-900 is an ATP-competitive ChK1 inhibitor with selective and oral activity.GNE-900 inhibits ChKl and ChK2 with IC50 values of 0.0011 and 1.5 μM, respectively.GNE-900 enhances DNA damage and induces apoptosis. GNE-900 has antitumor activity.
Smiles
C(#N)C=1C=C2C=3C(NC2=CN1)=NC=C(C3)C4=CC=C(CN5CCCCC5)C=C4
Molecular Formula
C23H21N5
Molecular Weight
367.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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