LY2780301
Product Specifications
CAS Number
1226801-23-5
Target
Akt|||Others
Related Pathways
Others|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling
Bioactivity
LY2780301 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor LY2780301 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway, thereby leading to inhibition of cell proliferation and the induction of apoptosis in tumor cells. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.
Smiles
C(CN(C)C)N1C(=NC(=C1)C2=CC(C(F)(F)F)=C(F)C=C2)C3CCN(CC3)C4=C5C(NC(=O)C5)=NC=N4
Molecular Formula
C25H27F4N7O
Molecular Weight
517.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/BC583BEE-ACCE-4346-9C28-6FB5C8D27B63/T71188
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6491486-01 0.2 mL
p53 (S15) (Cellular Tumor Antigen p53, Tumor Suppressor p53, Phosphoprotein p53, Antigen NY-CO-13, TP53, P53) (Azide free) (HRP)
Ask
View Details MBS6491486-02 5x 0.2 mL
p53 (S15) (Cellular Tumor Antigen p53, Tumor Suppressor p53, Phosphoprotein p53, Antigen NY-CO-13, TP53, P53) (Azide free) (HRP)
Ask
View Details MBS1195565-01 0.02 mg (E-Coli)
Recombinant Salmonella arizonae Serine--tRNA ligase (serS)
Ask
View Details