PWT33597 mesylate
Product Specifications
CAS Number
1246203-36-0
Target
Others|||PI3K|||Apoptosis|||mTOR
Related Pathways
Others|||Apoptosis|||PI3K/Akt/mTOR signaling
Bioactivity
PWT33597, also known as VDC-597, is an orally bioavailable dual inhibitor of phosphatidylinositide 3-kinase (PI3K) alpha and mammalian target of rapamycin (mTOR) kinase with potential antineoplastic activity. PI3K alpha/mTOR dual inhibitor PWT33597 selectively inhibits both PI3K alpha kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in PI3K/mTOR-overexpressing tumor cells.
Smiles
CS(O)(=O)=O.COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)-c1ccc(NS(=O)(=O)CCN(C)C)cc1)N1CCOCC1
Molecular Formula
C27H34F2N8O7S2
Molecular Weight
684.7348
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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