PBS-1086
Product Specifications
CAS Number
1246668-32-5
Target
Others
Related Pathways
Others
Bioactivity
PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-?B pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines.
Smiles
OC1C2C(O2)C(=O)C=C1NC(=O)C3=CC=4C(NC3=O)=CC=CC4
Molecular Formula
C16H12N2O5
Molecular Weight
312.28
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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